Although there have been no FDA-approved indications yet for use of SARMs, researchers are still exploring the possible medical uses for these powerful chemicals. Basic research has concentrated on the pharmacokinetics and kinetics of these drugs, showing a lack of drug interactions at a great extent.
However, despite these promising results, researchers are now focusing on the use of best sarm for strength in more specific clinical studies. This will be conducted by using the Selective Androgen Receptor Modulator (SARM), which aims to regulate the androgen receptors in the brain, preventing androgenic hormone secretion as well as its subsequent accumulation in the brain cells.
This Chinese herbal medication has recently been subject to several clinical trials. The first such study was conducted by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), using the placebo-controlled, double-blind method. In this study, NIDDK scientists randomly assigned randomly a single test group of men to receive an oral andarine supplement (25 mg), and the other group of women to receive a placebo.
The result of this study showed that there was a significant difference between the groups in terms of treatment retention, area of effects, mean blood levels and change from baseline in terms of total body fat and insulin resistance. Moreover, this study showed that the mean blood levels of mandarins were higher than that of placebo. Furthermore, participants who took the test combination had higher insulin sensitivity, higher total body fat levels and a significant improvement in the insulin sensitivity index (ISI).
Another study conducted by the National Institute of Diabetes and Digestive and Kidney Diseases is also focusing on the use of sarms in the treatment of diabetes. The study was conducted using healthy men who were diagnosed with high blood cholesterol levels (LDL). Men who took the placebo also had significantly lower blood cholesterol levels (p> =.5) as compared to the men who took the testosterone (T) injections.
The results showed that there was a significant improvement in terms of BMI, but no significant change in total blood cholesterol levels. However, the results showed that there was a significant effect of the testosterone (T) on insulin resistance index. The researchers also concluded that these results showed that although there was a significant improvement in terms of BMI, there was no significant change in the ability of the participants to resist the development of type 2 diabetes.
The third research study that addressed the use of SARMs and testosterone in relation to fitness enthusiasts was also conducted by the University of Nebraska Medical Center. A sample of 10 male fitness enthusiasts, who were between the ages of 22 and 35, were included in this study. The participants were asked to consume either placebo or sarms and to take their results regularly at home.
This study found that although there was no significant difference in BMI among the participants, there was a significant difference in the insulin resistance index. It was also found that the testosterone/sarms supplementation helped the participants to increase their muscle mass and to lose fat.
One of the limitations of this study was that the testosterone that was administered in the placebo arm had a higher concentration than the testosterone that was administered in the testosterone/sarms. The testosterone in this case was more effective in reducing the muscle wasting in males than in females.